Diabetic Retinopathy (DR) is a perfect precedent to gauge the extent of damage that diabetes can inflict. A new research indicates on how a preventive drug can help us in shedding our blindfold.
With a diabetic being twenty-five times more likely to go blind than someone without diabetes, it's high time that we illuminate this path.
Tinospora cordifolia: A torch in the dark
A recent study published in Food and Chemical Toxicology discusses the prevention and management of DR in experimental subjects. The journal also discusses the molecular mechanism of action and presents the following points:
- Prevention against cataract development.
- Decrease in angiogenic markers such as VGEF (Vascular endothelial growth factor) and PKC (Protein Kinase C) in diabetic retina.
- Protection of pancreatic islet structure.
- Prevention of retinal oxidative stress
- Anti-hyperglycemic effect
- Reduction of TNF-ALPHA (Tumour Necrosis Factor) and IL-1 (Interleukin 1) BETA level
Tinospora cordifolia in a nutshell reduces blood glucose and inhibits over expression of angiogenic and inflammatory mediators which are distinct markers of DR.
Tinospora cordifolia with Berberis aristata, Pterocarpus marsupium, Gymnema sylvestre, Rubia cordifolia, Trigonella foenum-graceum are key ingredients of BGR-34 which has been developed by Council of Scientific and Industrial Research (CSIR) for an effective management of diabetes. With new researches pouring in, BGR-34 along with the management of disease is also gaining credibility for the prevention of triopathic complications associated with diabetes.